Theses & Patents

Peptide Theses

1

CD99-PTPN12 axis suppresses actin cytoskeleton-mediated dimerization of epidermal growth factor receptor

Lee KJ,  Kim YR, Kim MS, JU HM, Choi BY, Lee HS,Jeoung DI, Moon KW, Kang DM, Choi J W, Yook JI, Hahn JH

Cancers 2020 Oct 12(10): 2895.

2

Alleviation of Ultraviolet-B Radiation-Induced Photoaging by a TNFR Antagonistic Peptide, TNFR2-SKE (2019)

Lee KJ, Park KH, Hahn JH

Molecules and Cell 2019 Feb 28;42(2):151-160.

3

CD99-derived agonist ligands inhibit fibronectin-induced activation of ¥â1 integrin through PKA/SHP2/ERK/PTPN12/FAK signaling pathway (2017)

Lee KJ, Kim YR, Yoo YH, Kim MS, Lee SH, Kim CG, Park KH, Jeoung DI, Lee HS, Ko IY, Hahn JH

Molecular and Cellular Biology 2017 Jul;37(14): e00675-16

4

Paired Ig-Like Type 2 Receptor-Derived Agonist Ligands Ameliorate Inflammatory Reactions by Downregulating ¥â1 Integrin Activity (2016)

Lee KJ, Lim D, Yoo YH, Park EJ, Lee SH, Yadav BK, Lee YK, Park JH, Kim D, Park KH, Hahn JH

Molecules and Cells 2016 Jul;39(7):557-65.

5

CD99 inhibits CD98-mediated ¥â1 integrin signaling through SHP2-mediated FAK dephosphorylation (2015)

Lee KJ, Yoo YH, Kim MS, Yadav BK, Kim Y, Lim D, Hwangbo C, Moon KW, Kim D, Jeoung D, Lee H, Lee JH, Hahn JH.

Exp Cell Res. Epub 2015 Jul 11.

6

YAC tripeptide of epidermal growth factor promotes the proliferation of HaCaT keratinocytes through activation of EGFR (2014)

Yoo YH, Kim YR, Kim MS, Lee KJ, Park KH, Hahn JH

BMB reports. 2014; 47(10): 581-586

7

A nuclear factor kappa B-derived inhibitor tripeptide inhibits UVB-induced photoaging process (2014)

Jee Eun Oh, Min Seo Kim, Woo-Kwang Jeon, Young Kwon Seo, Byung-Chul Kim, Jang Hee Hahn, Chang Seo Park

Journal of Dermatological Science 76 (2014) 196–205

8

The activation of CD99 inhibits cell-extracellular matrix adhesion by suppressing ¥â(1) integrin affinity (2012)

Lee KJ, Lee SH, Yadav BK, Ju HM, Kim MS, Park JH, Jeoung D, Lee H, Hahn JH.

BMB Rep. 45(3):159-64.

Peptide Patents

  • Wordwide Patents : Polypeptide inhibiting transmigration of leukocytes or growth and/or metastasis of cancer cells, and fusion protein thereof (US08207128) and other 6 patents
  • Domestic Patents : SFRP5-DERIVED PEPTIDE FRAGMENT AND COSMETIC COMPOSITION FOR SKIN WHITENING CONTAINING SAME(Korea Patent 1015726060000) and 13others